Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557116 | 0.87 | SIGMAR1 (0.52) | SIGMAR1AVPR1A | |
| SCHEMBL20275428 | 0.85 | SIGMAR1 (0.46) | SIGMAR1AVPR1A | |
| SCHEMBL7431299 | 0.80 | GRIN1 (0.61) | SIGMAR1 | |
| SCHEMBL12964441 | 0.79 | SIGMAR1 (0.52) | SIGMAR1AVPR1A | |
| SCHEMBL8553572 | 0.79 | SIGMAR1 (0.52) | SIGMAR1AVPR1A | |
| SCHEMBL7433636 | 0.79 | GRIN1 (0.63) | — | |
| SCHEMBL7430981 | 0.78 | GRIN1 (0.61) | SIGMAR1 | |
| SCHEMBL7436253 | 0.77 | SIGMAR1 (0.60) | SIGMAR1 | |
| SCHEMBL8014953 | 0.76 | SIGMAR1 (0.63) | SIGMAR1 | |
| SCHEMBL8556090 | 0.76 | AVPR1A (0.41) | SIGMAR1AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649407-B1 | DIMERIC PIPERIDINE, TETRAHYDROPYRIDINE AND PIPERAZINE DERIVATIVES | LUNDBECK & CO AS H (DK) | 1998-08-05 | — | — | EP | disclosed |