Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | B3GNT2 | Q9NY97 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7416107 | 0.84 | KIF11 (0.46) | ALDH1A1KDM4EHPGDHSD17B10KMT2A | |
| SCHEMBL5981755 | 0.80 | CASP3 (0.51) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL5694483 | 0.80 | CASP3 (0.54) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL19997297 | 0.79 | CASP3 (0.50) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL16380980 | 0.76 | CASP3 (0.54) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL10986953 | 0.75 | RARB (0.48) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL10985937 | 0.75 | RARB (0.48) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL10983069 | 0.75 | RARB (0.48) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL11094721 | 0.75 | RARB (0.48) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL10987508 | 0.75 | RARB (0.48) | CASP3SENP8SENP7SENP6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |