Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9248136 | 0.85 | NPC1 (0.55) | SMN1; SMN2NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL1985055 | 0.83 | L3MBTL1 (0.60) | SMN1; SMN2NPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL9578539 | 0.83 | MAPT (0.51) | SMN1; SMN2NPC1RAB9AL3MBTL1GRM4 | |
| SCHEMBL8555470 | 0.83 | HTT (0.54) | SMN1; SMN2NPC1RAB9AGRM4KDM4E | |
| SCHEMBL12422212 | 0.82 | L3MBTL1 (0.44) | L3MBTL1GRM4MAPTMAOBGAA | |
| Bicarbonate SCHEMBL27771212 | 0.82 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL6523003 | 0.81 | MAOB (0.62) | SMN1; SMN2NPC1RAB9AKMT2AMAPT | |
| SCHEMBL2714295 | 0.81 | MAOB (0.62) | SMN1; SMN2NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL12422213 | 0.81 | MAOB (0.49) | L3MBTL1MAPTMAOBTSHRGAA | |
| SCHEMBL9147011 | 0.80 | MAPT (0.56) | SMN1; SMN2NPC1RAB9AL3MBTL1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2338059-B1 | Ligands for aggregated tau molecules | WISTA LAB LTD (SG) | 2015-04-08 | — | — | EP | disclosed |
| US-8895313-B2 | Ligands for aggregated tau molecules | WISTA LABORATORIES LTD. (SG) | 2014-11-25 | — | — | US | disclosed |
| US-8895313-B2 | Ligands for aggregated tau molecules | WISTA LABORATORIES LTD. (SG) | 2014-11-25 | — | — | US | disclosed |
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. | 2011-07-14 | — | — | US | disclosed |
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. | 2011-07-14 | — | — | US | disclosed |
| WO-2010034982-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | WISTA LABORATORIES LTD. (SG) | 2010-04-01 | — | — | WO | disclosed |
| EP-0617031-B1 | Orally active azole derivates | URIACH & CIA SA J (ES) | 1998-09-16 | — | — | EP | disclosed |
| US-5760245-A | FUNGICIDES | J. URIACH & CIA S.A. (ES) | 1998-06-02 | — | — | US | disclosed |
| US-5646294-A | FUNGICIDES | J. URIACH & CIA. S.A. (ES) | 1997-07-08 | — | — | US | disclosed |
| US-5478826-A | Fungicides for human, animal and plants | J. URIACH & CIA. S.A. (ES) | 1995-12-26 | — | — | US | disclosed |
| US-5023380-A | Monomer for thermoplastic resin | THE DOW CHEMICAL COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0428708-A1 | PROCESS FOR PREPARING A POLYMER HAVING PERFLUOROCYCLOBUTANE RINGS AND POLYMERS CONTAINING PERFLUOROCYCLOBUTANE RINGS. | DOW CHEMICAL CO (US) | 1991-05-29 | — | — | EP | disclosed |
| EP-0428709-A1 | REACTIVE COMPOUNDS CONTAINING PERFLUOROVINYL GROUPS. | DOW CHEMICAL CO (US) | 1991-05-29 | — | — | EP | disclosed |
| EP-0428706-A1 | PERFLUOROVINYL COMPOUNDS. | DOW CHEMICAL CO (US) | 1991-05-29 | — | — | EP | disclosed |
| WO-1990015042-A2 | REACTIVE COMPOUNDS CONTAINING PERFLUOROVINYL GROUPS | THE DOW CHEMICAL COMPANY (US) | 1990-12-13 | — | — | WO | disclosed |
| WO-1990015043-A2 | PERFLUOROVINYL COMPOUNDS | THE DOW CHEMICAL COMPANY (US) | 1990-12-13 | — | — | WO | disclosed |
| WO-1990015082-A1 | PROCESS FOR PREPARING A POLYMER HAVING PERFLUOROCYCLOBUTANE RINGS AND POLYMERS CONTAINING PERFLUOROCYCLOBUTANE RINGS | THE DOW CHEMICAL COMPANY (US) | 1990-12-13 | — | — | WO | disclosed |
| US-4009208-A | N,N'-HEPTAMETHYLENEBIS(4-METHOXYBENZAMIDE) | STERLING DRUG INC. (US) | 1977-02-22 | — | — | US | disclosed |
| US-3996280-A | INTERMEDIATES FOR LOCAL ANESTHETICS AND ARRHYTHMICS | RIKER LABORATORIES, INC. (US) | 1976-12-07 | — | — | US | disclosed |
| US-3960945-A | 4-[-(Alkoxy or polyhaloalkoxy)-benzamido]cyclohexanones | STERLING DRUG INC. (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171739-A1 | LIGANDS FOR AGGREGATED TAU MOLECULES | MAPT, PRNP, MAP4 | SMN1; SMN2 1022/4885NPC1 1265/4885RAB9A 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.