Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14033159 | 0.93 | GAA (0.60) | NPC1RAB9ASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL1985055 | 0.86 | L3MBTL1 (0.60) | NPC1RAB9ASMN1; SMN2L3MBTL1SRD5A2 | |
| Bicarbonate SCHEMBL27771212 | 0.85 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL2714295 | 0.85 | MAOB (0.62) | NPC1RAB9ASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL6523003 | 0.85 | MAOB (0.62) | NPC1RAB9ASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8553712 | 0.85 | SMN1; SMN2 (0.52) | NPC1RAB9ASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL9578483 | 0.83 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL498377 | 0.82 | ALDH1A1 (0.56) | NPC1RAB9ASMN1; SMN2L3MBTL1GAA | |
| SCHEMBL21434732 | 0.82 | ALDH1A1 (0.62) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL10498948 | 0.82 | MAPT (0.66) | NPC1RAB9ASMN1; SMN2L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103842355-A | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS INC | 2014-06-04 | — | — | CN | claimed |
| CN-103764646-A | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS INC | 2014-04-30 | — | — | CN | claimed |
| CN-103842355-A | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS INC | 2014-06-04 | — | — | CN | disclosed |
| CN-103764646-A | Metalloenzyme inhibitor compounds | VIAMET PHARMACEUTICALS INC | 2014-04-30 | — | — | CN | disclosed |
| US-5382687-A | Electrography | HITACHI CHEMICAL COMPANY LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| EP-0448389-B1 | Enamine derivatives and their use in electrophotographic member | HITACHI CHEMICAL CO LTD (JP) | 1994-12-14 | — | — | EP | disclosed |
| US-5272030-A | Electrophotographic member comprising enamine derivatives | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1993-12-21 | — | — | US | disclosed |
| EP-0448389-A1 | Enamine derivatives and their use in electrophotographic member | Hitachi Chemical Co., Ltd. (JP) | 1991-09-25 | — | — | EP | disclosed |
| US-4888340-A | Insecticides pyrazolines, compositions and use | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-12-19 | — | — | US | disclosed |