Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553865 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2HTTTSHRL3MBTL1ALDH1A1 | |
| SCHEMBL3305432 | 0.79 | L3MBTL1 (0.34) | L3MBTL1ALDH1A1PHGDHALDH2MGLL | |
| SCHEMBL3305422 | 0.79 | L3MBTL1 (0.34) | L3MBTL1ALDH1A1PHGDHALDH2MGLL | |
| SCHEMBL11787909 | 0.77 | HTT (0.46) | SMN1; SMN2HTTTSHRPOLBLMNA | |
| SCHEMBL11787914 | 0.77 | HTT (0.46) | SMN1; SMN2HTTTSHRPOLBLMNA | |
| SCHEMBL3306859 | 0.77 | F2 (0.37) | L3MBTL1ALDH1A1PHGDHALDH2MGLL | |
| SCHEMBL3306866 | 0.77 | F2 (0.37) | L3MBTL1ALDH1A1PHGDHALDH2MGLL | |
| SCHEMBL5274271 | 0.77 | HTT (0.46) | SMN1; SMN2HTTTSHRL3MBTL1ALDH1A1 | |
| SCHEMBL8557483 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTTSHRALDH1A1FAAH | |
| SCHEMBL14034172 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2HTTTSHRALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0503958-B1 | Heterocyclic compounds and their production | NIPPON PAINT CO LTD (JP) | 1998-09-23 | — | — | EP | disclosed |
| US-5496943-A | USING UNSATURATED ACYLISOCYANATE COMPOUNDS TO FORM OXAZOLINES, PYRANS WITH AMINOCARBONYLHETERO SUBSTITUTION AND GLUTARIMIDE DERIVATIVES AS CHEMICAL INTERMEDIATES | NIPPON PAINT CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0503958-A2 | Heterocyclic compounds and their production | Nippon Paint Co., Ltd. (JP) | 1992-09-16 | — | — | EP | disclosed |
| US-4188341-A | Process for the production of (substituted) 2,6-dimethylanilines | CIBA-GEIGY CORPORATION (US) | 1980-02-12 | — | — | US | disclosed |