Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348992 | 0.88 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL5594237 | 0.84 | PTGS2 (0.84) | PTGS2PTGS1 | |
| SCHEMBL8350251 | 0.81 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL8556910 | 0.81 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL6149806 | 0.81 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL8622571 | 0.80 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL8025367 | 0.80 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL7860659 | 0.78 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL5594195 | 0.78 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8025612 | 0.77 | PTGS2 (0.69) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0880504-A1 | HETEROCYCLO-SUBSTITUTED IMIDAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-12-02 | — | — | EP | claimed |
| WO-1997027181-A1 | HETEROCYCLO-SUBSTITUTED IMIDAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-07-31 | — | — | WO | claimed |