Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348992 | 0.91 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL7773789 | 0.91 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL8346348 | 0.89 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL6149806 | 0.87 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL8350251 | 0.81 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL8553900 | 0.80 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL7860659 | 0.79 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL8622571 | 0.78 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL8347217 | 0.77 | PTGS2 (0.69) | PTGS2PTGS1 | |
| Sulfamide SCHEMBL4638575 | 0.76 | PTGS2 (0.80) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979077-A1 | METHOD OF USING CYCLOOXYGENASE-2 INHIBITORS IN THE PREVENTION OF CARDIOVASCULAR DISORDERS | G.D. Searle & Co. (US) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047509-A1 | METHOD OF USING CYCLOOXYGENASE-2 INHIBITORS IN THE PREVENTION OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1998-10-29 | — | — | WO | disclosed |