Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.54 |
| ▸ | CCKBR | P32239 | 10/20 | 0.51 |
| ▸ | BRD4 | O60885 | 5/20 | 0.46 |
| ▸ | BRD2 | P25440 | 5/20 | 0.46 |
| ▸ | BRD3 | Q15059 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554873 | 0.88 | SENP1 (0.53) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL8556281 | 0.84 | SENP1 (0.59) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL8558106 | 0.84 | SENP1 (0.49) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL9868359 | 0.83 | SENP1 (0.67) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL7544210 | 0.81 | SENP1 (0.46) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL7549270 | 0.81 | SENP1 (0.46) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL7549273 | 0.81 | SENP1 (0.46) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL7544205 | 0.81 | SENP1 (0.46) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL9256442 | 0.81 | SCN9A (0.61) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL9256454 | 0.81 | SCN9A (0.61) | SENP1CCKBRBRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |