Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.67 |
| ▸ | CCKBR | P32239 | 11/20 | 0.67 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.56 |
| ▸ | BRD4 | O60885 | 4/20 | 0.56 |
| ▸ | BRD2 | P25440 | 4/20 | 0.56 |
| ▸ | BRD3 | Q15059 | 4/20 | 0.56 |
| ▸ | CCKAR | P32238 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939417 | 0.86 | SENP1 (0.79) | SENP1CCKBRSCN9ABRD4BRD2 | |
| SCHEMBL8711263 | 0.86 | SENP1 (0.79) | SENP1CCKBRSCN9ABRD4BRD2 | |
| SCHEMBL8711261 | 0.86 | SENP1 (0.79) | SENP1CCKBRSCN9ABRD4BRD2 | |
| SCHEMBL9865718 | 0.84 | SENP1 (0.76) | SENP1CCKBRSCN9ABRD4BRD2 | |
| SCHEMBL1574250 | 0.84 | SENP1 (0.70) | SENP1CCKBRSCN9ABRD4BRD2 | |
| SCHEMBL1574248 | 0.84 | SENP1 (0.70) | SENP1CCKBRSCN9ABRD4BRD2 | |
| SCHEMBL1574028 | 0.84 | SENP1 (0.70) | SENP1CCKBRSCN9ABRD4BRD2 | |
| SCHEMBL1574029 | 0.84 | SENP1 (0.70) | SENP1CCKBRSCN9ABRD4BRD2 | |
| SCHEMBL6940307 | 0.84 | SENP1 (0.73) | SENP1CCKBRSCN9ABRD4BRD2 | |
| SCHEMBL1574343 | 0.84 | SENP1 (0.75) | SENP1CCKBRSCN9ABRD4BRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004741-A | Cholecystokinin(CCK); Treating Disorders Of The Gastrointestinal Tract, Central Nervous System And Of The Appetite Of Animals | MERCK & CO., INC. (US) | 1991-04-02 | — | — | US | disclosed |
| US-4820834-A | Benzodiazepine analogs | MERCK & CO., INC. (US) | 1989-04-11 | — | — | US | disclosed |
| EP-0284256-A1 | Benzodiazepine analogs | MERCK & CO. INC. (US) | 1988-09-28 | — | — | EP | disclosed |