Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.76 |
| ▸ | HTR2C | P28335 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21300990 | 0.87 | HTR2A (0.78) | HTR2AHTR2CKMT2AHPGDLMNA | |
| SCHEMBL8559870 | 0.86 | HTR2A (0.76) | HTR2AHTR2CKMT2AHPGDLMNA | |
| SCHEMBL16451345 | 0.86 | HTR2A (1.00) | HTR2AHTR2CKMT2AHPGDLMNA | |
| SCHEMBL1913967 | 0.85 | HTR2A (0.87) | HTR2AHTR2CKMT2AHPGDLMNA | |
| SCHEMBL8552605 | 0.82 | HTR2A (0.69) | HTR2AHTR2CKMT2AHPGDLMNA | |
| SCHEMBL8557333 | 0.82 | HTR2A (0.69) | HTR2AHTR2CKMT2AHPGDLMNA | |
| SCHEMBL8552143 | 0.80 | HTR2C (0.66) | HTR2AHTR2CKMT2AHPGDLMNA | |
| SCHEMBL8556552 | 0.80 | HTR2A (0.49) | HTR2AHTR2CKMT2AHPGDLMNA | |
| SCHEMBL8554628 | 0.78 | HTR2A (0.64) | HTR2AHTR2CKMT2AHPGDLMNA | |
| SCHEMBL8555442 | 0.76 | LIPG (0.47) | HTR2AHTR2CKMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529452-B1 | 1,7-Condensed 3-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SOLVAY PHARM GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5324725-A | Antiinflammatory agent, antiallergen | KALI-CHEMIE PHARMA GMBH (DE) | 1994-06-28 | — | — | US | disclosed |
| CN-1069732-A | 1, the 2-that 7-a pair of horses going side by side is closed (piperazine alkyl) indole derivatives and preparation method and intermediate product and the medicament that contains these compounds | KALI CHEMIE PHARMA GMBH (DE) | 1993-03-10 | — | — | CN | disclosed |
| EP-0529452-A2 | 1,7-Condensed 2-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1993-03-03 | — | — | EP | disclosed |