Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553506 | 0.88 | LIPG (0.47) | LIPGHTR2AHTR2CMAPK1KMT2A | |
| SCHEMBL8556552 | 0.83 | HTR2A (0.49) | LIPGHTR2AHTR2CMAPK1KMT2A | |
| SCHEMBL8558110 | 0.77 | HTR2A (0.44) | HTR2AHTR2CMAPK1KMT2AMEN1 | |
| SCHEMBL8553952 | 0.76 | HTR2A (0.76) | LIPGHTR2AHTR2CKMT2AMEN1 | |
| SCHEMBL8554253 | 0.74 | ALOX5 (0.77) | LIPGHTR2AHTR2CALOX5DRD2 | |
| SCHEMBL21300990 | 0.64 | HTR2A (0.78) | LIPGHTR2AHTR2CMAPK1KMT2A | |
| SCHEMBL14198328 | 0.64 | ALOX5 (0.50) | HTR2AHTR2CMAPK1KMT2AMEN1 | |
| SCHEMBL16451345 | 0.63 | HTR2A (1.00) | LIPGHTR2AHTR2CKMT2AMEN1 | |
| SCHEMBL8559870 | 0.63 | HTR2A (0.76) | LIPGHTR2AHTR2CKMT2AMEN1 | |
| SCHEMBL28231325 | 0.63 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529452-B1 | 1,7-Condensed 3-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SOLVAY PHARM GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5324725-A | Antiinflammatory agent, antiallergen | KALI-CHEMIE PHARMA GMBH (DE) | 1994-06-28 | — | — | US | disclosed |
| EP-0529452-A2 | 1,7-Condensed 2-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1993-03-03 | — | — | EP | disclosed |