Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304089 | 0.87 | MEN1 (0.52) | MEN1KMT2AMAPK1HTR2AHTR2C | |
| SCHEMBL8553141 | 0.82 | MEN1 (0.45) | MEN1KMT2AMAPK1HTR2AHTR2C | |
| SCHEMBL8557902 | 0.77 | KMT2A (0.45) | MEN1KMT2AMAPK1HTR2AHTR2C | |
| SCHEMBL8557855 | 0.77 | ALOX5 (0.55) | MEN1KMT2AMAPK1ALOX5HPGD | |
| SCHEMBL8554628 | 0.76 | HTR2A (0.64) | MEN1KMT2AMAPK1HTR2AHTR2C | |
| SCHEMBL8555671 | 0.73 | ALOX5 (0.74) | MEN1KMT2AMAPK1HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL8554866 | 0.73 | ALOX5 (0.73) | MEN1KMT2AMAPK1HTR2AHTR2C | |
| SCHEMBL8556575 | 0.72 | HTR2A (0.60) | MEN1KMT2AHTR2AHTR2CMCL1 | |
| SCHEMBL9303580 | 0.68 | MAPK1 (0.56) | MEN1KMT2AMAPK1HTR2AHTR2C | |
| SCHEMBL9302647 | 0.67 | MAPK1 (0.55) | MEN1KMT2AMAPK1HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529452-B1 | 1,7-Condensed 3-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SOLVAY PHARM GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5324725-A | Antiinflammatory agent, antiallergen | KALI-CHEMIE PHARMA GMBH (DE) | 1994-06-28 | — | — | US | disclosed |
| EP-0529452-A2 | 1,7-Condensed 2-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1993-03-03 | — | — | EP | disclosed |