Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.36 |
| ▸ | BCHE | P06276 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557900 | 0.79 | — | — | |
| SCHEMBL623356 | 0.74 | PTGS2 (0.44) | ACHEPTGS2BCHENPC1RAB9A | |
| SCHEMBL10919706 | 0.73 | ALDH1A1 (0.34) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL8829945 | 0.70 | PTGS2 (0.39) | ACHEPTGS2BCHENPC1RAB9A | |
| SCHEMBL6394314 | 0.70 | PTGS2 (0.57) | ACHEPTGS2BCHENPC1RAB9A | |
| SCHEMBL790880 | 0.68 | — | — | |
| SCHEMBL9579378 | 0.68 | — | — | |
| SCHEMBL8829957 | 0.68 | PTGS2 (0.37) | ACHEPTGS2BCHENPC1RAB9A | |
| SCHEMBL2066513 | 0.67 | — | — | |
| SCHEMBL1413359 | 0.66 | PTGS2 (0.44) | ACHEPTGS2BCHENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582304-B1 | Methods of producing amino butene derivatives | FUJIREBIO KK (JP) | 1998-04-01 | — | — | EP | claimed |
| US-5616711-A | REACTING BUTENE DERIVATIVE TO AN AMIDE DERIVATIVE; USEFUL AS INTERMEDIATES FOR PRODUCING ANTIULCER DRUGS | FUJIREBIO INC. (JP) | 1997-04-01 | — | — | US | claimed |
| EP-0582304-A2 | Methods of producing amino butene derivatives | FUJIREBIO Inc. (JP) | 1994-02-09 | — | — | EP | claimed |
| EP-0582304-B1 | Methods of producing amino butene derivatives | FUJIREBIO KK (JP) | 1998-04-01 | — | — | EP | disclosed |
| US-5616711-A | REACTING BUTENE DERIVATIVE TO AN AMIDE DERIVATIVE; USEFUL AS INTERMEDIATES FOR PRODUCING ANTIULCER DRUGS | FUJIREBIO INC. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0582304-A2 | Methods of producing amino butene derivatives | FUJIREBIO Inc. (JP) | 1994-02-09 | — | — | EP | disclosed |