Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.50 |
| ▸ | PLAU | P00749 | 10/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374823 | 0.90 | PLAU (0.47) | PLGPLAUALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8547382 | 0.88 | PLAU (0.46) | PLGPLAUALDH1A1MEN1KMT2A | |
| SCHEMBL8549276 | 0.85 | PLAU (0.43) | PLGPLAUKMT2APLAT | |
| SCHEMBL8372792 | 0.85 | PLAU (0.43) | PLGPLAUALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8551595 | 0.84 | PLAU (0.42) | PLGPLAUALDH1A1MEN1KMT2A | |
| SCHEMBL8552274 | 0.82 | PLAU (0.40) | PLGPLAU | |
| Hydrochloric Acid SCHEMBL8549377 | 0.82 | PLG (0.55) | PLGPLAUALDH1A1MEN1KMT2A | |
| SCHEMBL8554002 | 0.79 | PLAU (0.44) | PLGPLAUALDH1A1MEN1KMT2A | |
| SCHEMBL8549556 | 0.79 | PLAU (0.44) | PLGPLAUALDH1A1MEN1KMT2A | |
| SCHEMBL8371541 | 0.77 | PLAU (0.42) | PLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |