Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 10/20 | 0.43 |
| ▸ | PLG | P00747 | 3/20 | 0.39 |
| ▸ | ATP4A | P20648 | 2/20 | 0.38 |
| ▸ | ATP4B | P51164 | 2/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8372792 | 0.85 | PLAU (0.43) | PLAUPLGATP4AATP4BSMO | |
| SCHEMBL8554034 | 0.85 | PLG (0.50) | PLAUPLGPLATKMT2A | |
| Hydrochloric Acid SCHEMBL8551595 | 0.84 | PLAU (0.42) | PLAUPLGATP4AATP4BSMO | |
| SCHEMBL8552274 | 0.82 | PLAU (0.40) | PLAUPLGHSD11B1 | |
| SCHEMBL8374823 | 0.82 | PLAU (0.47) | PLAUPLGPLATKMT2A | |
| SCHEMBL8549556 | 0.81 | PLAU (0.44) | PLAUPLGHTR3EHTR3BHTR3A | |
| Hydrochloric Acid SCHEMBL8547382 | 0.81 | PLAU (0.46) | PLAUPLGPLATKMT2A | |
| SCHEMBL8549331 | 0.78 | HSD11B1 (0.42) | HSD11B1SMOSMN1; SMN2GAAKMT2A | |
| SCHEMBL8554002 | 0.76 | PLAU (0.44) | PLAUPLGATP4AATP4BSMO | |
| SCHEMBL8549269 | 0.76 | HSD11B1 (0.34) | HSD11B1SMOSMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |