Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553780 | 0.80 | NPC1 (0.36) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL9075670 | 0.79 | NR1I2 (0.31) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8603712 | 0.79 | NR1I2 (0.37) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8557958 | 0.77 | NR1I2 (0.39) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8555548 | 0.77 | LMNA (0.40) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8661865 | 0.77 | NPC1 (0.34) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8824437 | 0.76 | — | — | |
| SCHEMBL8604570 | 0.76 | HDAC6 (0.38) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL8551826 | 0.76 | FFAR4 (0.44) | MEN1KMT2AFFAR1USP2ALOX15 | |
| SCHEMBL8553057 | 0.76 | KMT2A (0.34) | NPC1NFKB1RAB9ANFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |