Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | NCF1 | P14598 | 2/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8558963 | 0.99 | HTT (0.33) | GRM5HTR3ANCF1SSTR2HRH3 | |
| SCHEMBL8555441 | 0.80 | DYRK1A (0.39) | KDM4EALDH1A1HTT | |
| SCHEMBL28719464 | 0.73 | NCF1 (0.46) | GRM5NCF1HCRTR1KDM4EALDH1A1 | |
| SCHEMBL8554652 | 0.71 | HSD17B10 (0.34) | GRM5NCF1KDM4EALDH1A1GLA | |
| SCHEMBL8554096 | 0.69 | HRH3 (0.39) | NCF1HRH3KDM4EALDH1A1GLA | |
| SCHEMBL10736064 | 0.69 | GBA1 (0.44) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8558959 | 0.68 | HRH3 (0.38) | HRH3KDM4EALDH1A1GLAGAA | |
| SCHEMBL6723993 | 0.68 | EGFR (0.51) | NCF1KDM4EALDH1A1GLAHPGD | |
| SCHEMBL5421326 | 0.61 | NCF1 (0.40) | GRM5NCF1KDM4EALDH1A1GLA | |
| SCHEMBL4733753 | 0.61 | NCF1 (0.50) | NCF1KDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | claimed |
| EP-0543307-A2 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-05-26 | — | — | EP | claimed |
| EP-0543307-A2 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |