Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.35 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.35 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556306 | 0.82 | KDR (0.34) | DYRK1ADYRK1BPOLBMAPTSMN1; SMN2 | |
| SCHEMBL8554099 | 0.80 | GRM5 (0.33) | HTTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL8558963 | 0.79 | HTT (0.33) | SMN1; SMN2HTTKMT2AKDM4EALDH1A1 | |
| SCHEMBL8554052 | 0.77 | LMNA (0.37) | CTSBARPOLBMAPTKMT2A | |
| SCHEMBL28719466 | 0.76 | POLB (0.47) | DYRK1ADYRK1BCYP1A2POLBMAPT | |
| SCHEMBL8555439 | 0.72 | RAB9A (0.38) | CTSBARPOLBMAPTSMN1; SMN2 | |
| SCHEMBL8595610 | 0.67 | CTSB (0.39) | CTSBARMAPTSMN1; SMN2TNNI3 | |
| SCHEMBL4727431 | 0.66 | POLB (0.51) | CYP1A2POLBMAPTSMN1; SMN2HTT | |
| SCHEMBL28058588 | 0.66 | POLB (0.51) | CYP1A2POLBMAPTSMN1; SMN2HTT | |
| SCHEMBL5796165 | 0.66 | POLB (0.42) | CYP1A2CTSBPOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | claimed |
| JP-6184152-A | — | — | None | — | — | JP | disclosed |
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | disclosed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | disclosed |
| JP-H06184152-A | NEW COMPOUND, ITS PRODUCTION AND BRAIN FUNCTION IMPROVER USING THE SAME AS MAIN INGREDIENT | SANWA KAGAKU KENKYUSHO CO LTD | 1994-07-05 | — | — | JP | disclosed |
| EP-0543307-A2 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-05-26 | — | — | EP | disclosed |