Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | FABP6 | P51161 | 1/20 | 0.35 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556463 | 0.86 | HDAC1 (0.34) | GAASMN1; SMN2SCN8A | |
| SCHEMBL6979992 | 0.76 | SCN8A (0.36) | TSHRSCN8AMAPT | |
| SCHEMBL8824480 | 0.75 | SCN8A (0.38) | GRM5GAASCN8AMAPT | |
| SCHEMBL8824433 | 0.75 | SCN8A (0.38) | GAASCN8AMAPT | |
| SCHEMBL8663366 | 0.75 | SCN8A (0.47) | GRM5SMN1; SMN2LMNASCN8AMAPT | |
| SCHEMBL9089326 | 0.75 | SCN8A (0.36) | GAASCN8A | |
| SCHEMBL8552613 | 0.74 | NR1I2 (0.47) | GAAHTTKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL9090767 | 0.74 | SCN8A (0.35) | KMT2ASCN8A | |
| SCHEMBL8824523 | 0.73 | SCN8A (0.37) | GRM5HTTKMT2ASMN1; SMN2SCN8A | |
| SCHEMBL8992092 | 0.73 | SCN8A (0.39) | GRM5SCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| WO-1995031452-A1 | THERAPEUTIC PHENOXYALKYLAZOLES AND PHENOXYALKYLAZINES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |