Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.39 |
| ▸ | VNN1 | O95497 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663366 | 0.84 | SCN8A (0.47) | SCN8AGRM5 | |
| SCHEMBL8824480 | 0.82 | SCN8A (0.38) | SCN8AGRM5KCNH2EGLN2 | |
| SCHEMBL8824433 | 0.82 | SCN8A (0.38) | SCN8AKCNH2 | |
| SCHEMBL8824523 | 0.80 | SCN8A (0.37) | SCN8AGRM5KCNH2EGLN2 | |
| SCHEMBL8824506 | 0.80 | SCN8A (0.37) | SCN8AKCNH2 | |
| SCHEMBL8665185 | 0.79 | SCN8A (0.43) | SCN8A | |
| SCHEMBL8992101 | 0.79 | VNN1 (0.34) | VNN1CTDSP1 | |
| SCHEMBL8923501 | 0.77 | SCN8A (0.49) | SCN8AVNN1 | |
| SCHEMBL8922786 | 0.76 | SCN8A (0.42) | SCN8AGRM5 | |
| SCHEMBL8824421 | 0.76 | CTDSP1 (0.36) | SCN8AVNN1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514679-A | TREATMENT OF PICORNAVIRUS INFECTIONS | STERLING WINTHROP INC. (US) | 1996-05-07 | — | — | US | disclosed |