Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554117 | 0.86 | GRM5 (0.39) | SCN8ASMN1; SMN2GAA | |
| SCHEMBL6981536 | 0.79 | SCN8A (0.35) | SCN8ASMN1; SMN2KCNH2KDM4E | |
| SCHEMBL8824433 | 0.77 | SCN8A (0.38) | SCN8AKCNH2CYP3A4CYP2D6KDM4E | |
| SCHEMBL8555393 | 0.77 | NR1I2 (0.45) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL9087868 | 0.77 | SCN8A (0.34) | SCN8ANR1I2CYP3A4CYP2D6 | |
| SCHEMBL8553621 | 0.73 | NR1I2 (0.44) | NR1I2CYP3A4CYP2D6 | |
| SCHEMBL8553191 | 0.73 | NR1I2 (0.64) | HDAC1HDAC6NR1I2CYP3A4CYP2D6 | |
| SCHEMBL6979992 | 0.73 | SCN8A (0.36) | SCN8A | |
| SCHEMBL8663366 | 0.72 | SCN8A (0.47) | SCN8ASMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL8824480 | 0.72 | SCN8A (0.38) | SCN8AKCNH2NR1I2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |