Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.59 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.59 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 10/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554146 | 1.00 | CYSLTR1 (0.59) | CYSLTR1CYSLTR2GPBAR1ALOX5HDAC6 | |
| SCHEMBL8554770 | 0.87 | CYSLTR2 (0.44) | CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL8554759 | 0.87 | CYSLTR2 (0.44) | CYSLTR1CYSLTR2ALOX5 | |
| SCHEMBL8555246 | 0.86 | GPBAR1 (0.61) | CYSLTR1CYSLTR2GPBAR1ALOX5HDAC6 | |
| SCHEMBL8554925 | 0.86 | GPBAR1 (0.61) | CYSLTR1CYSLTR2GPBAR1ALOX5HDAC6 | |
| SCHEMBL8555104 | 0.85 | GPBAR1 (0.60) | CYSLTR1CYSLTR2GPBAR1ALOX5HDAC6 | |
| SCHEMBL8555687 | 0.85 | GPBAR1 (0.60) | CYSLTR1CYSLTR2GPBAR1ALOX5HDAC6 | |
| SCHEMBL7611388 | 0.80 | GPBAR1 (0.62) | CYSLTR1CYSLTR2GPBAR1ALOX5HDAC6 | |
| SCHEMBL7603712 | 0.79 | GPBAR1 (0.70) | CYSLTR1CYSLTR2GPBAR1ALOX5HDAC6 | |
| SCHEMBL14021543 | 0.77 | GPBAR1 (0.70) | CYSLTR1CYSLTR2GPBAR1ALOX5FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |