Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 12/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.58 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555246 | 1.00 | GPBAR1 (0.61) | GPBAR1ALOX5HDAC6CYSLTR1CYSLTR2 | |
| SCHEMBL8555687 | 0.99 | GPBAR1 (0.60) | GPBAR1ALOX5HDAC6CYSLTR1CYSLTR2 | |
| SCHEMBL8555104 | 0.99 | GPBAR1 (0.60) | GPBAR1ALOX5HDAC6CYSLTR1CYSLTR2 | |
| SCHEMBL8557021 | 0.87 | ALOX5 (0.52) | GPBAR1ALOX5HDAC6CYSLTR1CYSLTR2 | |
| SCHEMBL8554146 | 0.86 | CYSLTR1 (0.59) | GPBAR1ALOX5HDAC6CYSLTR1CYSLTR2 | |
| SCHEMBL8554159 | 0.86 | CYSLTR1 (0.59) | GPBAR1ALOX5HDAC6CYSLTR1CYSLTR2 | |
| SCHEMBL8557412 | 0.86 | ALOX5 (0.44) | GPBAR1ALOX5HDAC6CYSLTR1CYSLTR2 | |
| SCHEMBL8557396 | 0.86 | ALOX5 (0.44) | GPBAR1ALOX5HDAC6CYSLTR1CYSLTR2 | |
| SCHEMBL7603712 | 0.86 | GPBAR1 (0.70) | GPBAR1ALOX5HDAC6CYSLTR1CYSLTR2 | |
| SCHEMBL8552913 | 0.85 | ALOX5 (0.44) | GPBAR1ALOX5HDAC6CYSLTR1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | claimed |
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |