Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.44 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554770 | 1.00 | CYSLTR2 (0.44) | CYSLTR2CYSLTR1ALOX5ALOX5AP | |
| SCHEMBL8554146 | 0.87 | CYSLTR1 (0.59) | CYSLTR2CYSLTR1ALOX5 | |
| SCHEMBL8554159 | 0.87 | CYSLTR1 (0.59) | CYSLTR2CYSLTR1ALOX5 | |
| SCHEMBL8557412 | 0.87 | ALOX5 (0.44) | CYSLTR2CYSLTR1ALOX5ALOX5AP | |
| SCHEMBL8557396 | 0.87 | ALOX5 (0.44) | CYSLTR2CYSLTR1ALOX5ALOX5AP | |
| SCHEMBL8552934 | 0.86 | ALOX5 (0.44) | CYSLTR2CYSLTR1ALOX5ALOX5AP | |
| SCHEMBL8552913 | 0.86 | ALOX5 (0.44) | CYSLTR2CYSLTR1ALOX5ALOX5AP | |
| SCHEMBL8900532 | 0.82 | ALOX5 (0.48) | CYSLTR2CYSLTR1ALOX5ALOX5AP | |
| SCHEMBL8900513 | 0.82 | ALOX5 (0.48) | CYSLTR2CYSLTR1ALOX5ALOX5AP | |
| SCHEMBL8554762 | 0.77 | ALOX5 (0.48) | CYSLTR2CYSLTR1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5714488-A | FOR TREATMENT OF ALLERGIC AND INFLAMMATORY DISEASE STATES | ABBOTT LABORATORIES (US) | 1998-02-03 | — | — | US | disclosed |