Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene SCHEMBL8557034 | 0.82 | SMN1; SMN2 (0.51) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL4240804 | 0.78 | SMN1; SMN2 (0.55) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL13911781 | 0.78 | SMN1; SMN2 (0.55) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL28391104 | 0.77 | SMN1; SMN2 (0.53) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL6984427 | 0.71 | SMN1; SMN2 (0.56) | LMNAMEN1KMT2ASMN1; SMN2MAPT | |
| Biphenyl SCHEMBL8754510 | 0.71 | LMNA (0.44) | LMNASMN1; SMN2MAPTL3MBTL1GAA | |
| Biphenyl SCHEMBL3862996 | 0.69 | LMNA (0.57) | LMNASMN1; SMN2MAPTL3MBTL1GAA | |
| Tannin Pyrogallol SCHEMBL22288201 | 0.68 | LMNA (0.55) | LMNASMN1; SMN2MAPTL3MBTL1GAA | |
| Biphenyl SCHEMBL8087383 | 0.68 | LMNA (0.55) | LMNASMN1; SMN2MAPTL3MBTL1GAA | |
| Ethylene SCHEMBL140298 | 0.68 | LMNA (0.55) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567430-B1 | Substituted 1-Hydroxy-2,6-Diaryl-4-Piperidone Ketal Stabilizers | CIBA GEIGY AG (CH) | 1998-02-18 | — | — | EP | disclosed |
| EP-0567430-A1 | Substituted 1-Hydroxy-2,6-Diaryl-4-Piperidone Ketal Stabilizers | CIBA-GEIGY AG (CH) | 1993-10-27 | — | — | EP | disclosed |