Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 19/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8553079 | 0.87 | NPC1 (0.38) | GNRHR | |
| SCHEMBL8554205 | 0.77 | NPY1R (0.39) | — | |
| Trifluoroacetic Acid SCHEMBL8552498 | 0.77 | NPY1R (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL8554402 | 0.76 | NPY1R (0.43) | GNRHR | |
| Trifluoroacetic Acid SCHEMBL8555320 | 0.76 | NPY1R (0.42) | GNRHR | |
| Trifluoroacetic Acid SCHEMBL7690833 | 0.73 | NPY1R (0.55) | — | |
| Trifluoroacetic Acid SCHEMBL7690250 | 0.73 | NPY1R (0.66) | — | |
| Trifluoroacetic Acid SCHEMBL8554400 | 0.67 | NPY1R (0.44) | — | |
| SCHEMBL8555586 | 0.65 | RAB9A (0.47) | — | |
| Trifluoroacetic Acid SCHEMBL8555689 | 0.65 | NPY1R (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |