Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | PPID | Q08752 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10458424 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2APPIDRAB9A | |
| SCHEMBL4912299 | 0.77 | MEN1 (0.54) | SMN1; SMN2MEN1KMT2APPIDRAB9A | |
| SCHEMBL10516677 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1KMT2APPIDRAB9A | |
| SCHEMBL12532261 | 0.76 | SMN1; SMN2 (0.65) | SMN1; SMN2MEN1KMT2APPIDRAB9A | |
| Malonic Acid Diethyl Ester SCHEMBL14880154 | 0.75 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2APPIDRAB9A | |
| SCHEMBL62893 | 0.75 | POLB (0.60) | SMN1; SMN2MEN1KMT2APPIDRAB9A | |
| Toluene SCHEMBL28067808 | 0.75 | PPID (0.59) | SMN1; SMN2PPIDRAB9ANPC1LMNA | |
| Hydrochloric Acid SCHEMBL133175 | 0.74 | POLB (0.59) | SMN1; SMN2MEN1KMT2APPIDRAB9A | |
| Malonic Acid Diethyl Ester SCHEMBL28126913 | 0.74 | MEN1 (0.54) | SMN1; SMN2MEN1KMT2APPIDRAB9A | |
| SCHEMBL8819571 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2MEN1KMT2APPIDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815108-A1 | CYCLIC UREA HIV PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |