Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 16/20 | 0.66 |
| ▸ | FPR3 | P25089 | 11/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2682336 | 1.00 | FPR2 (0.66) | FPR2FPR3PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL855247 | 0.87 | FPR2 (0.60) | FPR2FPR3 | |
| SCHEMBL2683402 | 0.87 | FPR2 (0.60) | FPR2FPR3 | |
| SCHEMBL2682272 | 0.86 | FPR2 (0.66) | FPR2FPR3PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL857602 | 0.86 | FPR2 (0.66) | FPR2FPR3PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL2683189 | 0.85 | FPR2 (0.62) | FPR2FPR3PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL855464 | 0.85 | FPR2 (0.62) | FPR2FPR3PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL856355 | 0.84 | FPR2 (0.63) | FPR2FPR3PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL2682650 | 0.84 | FPR2 (0.63) | FPR2FPR3PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL855540 | 0.82 | FPR2 (0.63) | FPR2FPR3PKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432760-A1 | BRIDGED SPIRO [2.4]HEPTANE DERIVATIVES AS ALX RECEPTOR AND/OR FPRL2 AGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2012-03-28 | — | — | EP | disclosed |