Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 17/20 | 0.63 |
| ▸ | FPR3 | P25089 | 12/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2681991 | 1.00 | FPR2 (0.63) | FPR2FPR3PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL2682240 | 0.87 | FPR2 (0.60) | FPR2FPR3PKM | |
| SCHEMBL856281 | 0.87 | FPR2 (0.60) | FPR2FPR3PKM | |
| SCHEMBL855432 | 0.82 | FPR2 (0.66) | FPR2FPR3PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL2682336 | 0.82 | FPR2 (0.66) | FPR2FPR3PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL855464 | 0.81 | FPR2 (0.62) | FPR2FPR3PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL2683189 | 0.81 | FPR2 (0.62) | FPR2FPR3PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL855746 | 0.80 | FPR2 (0.68) | FPR2FPR3 | |
| SCHEMBL2682633 | 0.80 | FPR2 (0.68) | FPR2FPR3 | |
| SCHEMBL2684065 | 0.78 | FPR3 (1.00) | FPR2FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432760-A1 | BRIDGED SPIRO [2.4]HEPTANE DERIVATIVES AS ALX RECEPTOR AND/OR FPRL2 AGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2012-03-28 | — | — | EP | disclosed |