Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.75 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13860443 | 0.86 | GAA (1.00) | GAAMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8555328 | 0.83 | GAA (0.69) | GAAMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL1063608 | 0.80 | MAPT (0.74) | GAAMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8556236 | 0.78 | GAA (0.71) | GAAMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL8555695 | 0.78 | GAA (0.65) | GAAMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL2546236 | 0.76 | GAA (0.68) | GAAMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL6205515 | 0.76 | GAA (0.56) | GAAMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL31194507 | 0.75 | GAA (0.40) | GAAMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL11546523 | 0.75 | GAA (0.65) | GAAMAPTLMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7359402 | 0.74 | GAA (0.60) | GAAMAPTLMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |