Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555695 | 0.85 | GAA (0.65) | GAAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL1063608 | 0.75 | MAPT (0.74) | GAAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL13860443 | 0.75 | GAA (1.00) | GAAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL8554372 | 0.74 | GAA (0.75) | GAAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL12100341 | 0.72 | KDM4E (0.60) | GAAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL7355477 | 0.72 | STS (0.40) | LMNASMN1; SMN2ALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL8556236 | 0.71 | GAA (0.71) | GAAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL13664157 | 0.70 | GAA (0.58) | GAAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL8555328 | 0.70 | GAA (0.69) | GAAMAPTLMNAKMT2AMEN1 | |
| SCHEMBL11546523 | 0.70 | GAA (0.65) | GAAMAPTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000053649-A | SULFONYLUREIDOPYRAZOLE DERIVATIVE | SUMITOMO PHARMACEUT CO LTD | 2000-02-22 | — | — | JP | disclosed |