Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554372 | 0.83 | GAA (0.75) | GAAMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL13860443 | 0.82 | GAA (1.00) | GAAMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL1063608 | 0.79 | MAPT (0.74) | GAAMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL8556236 | 0.77 | GAA (0.71) | GAAMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL2546236 | 0.75 | GAA (0.68) | GAAMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL11546523 | 0.74 | GAA (0.65) | GAAMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL8550425 | 0.73 | NPC1 (0.39) | GAALMNASMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL8555695 | 0.72 | GAA (0.65) | GAAMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL3994806 | 0.71 | GAA (0.61) | GAAMAPTLMNASMN1; SMN2MEN1 | |
| SCHEMBL2743087 | 0.71 | GAA (0.61) | GAAMAPTLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |