SCHEMBL8554418

SCHEMBL8554418

c1ccc2c(c1)C1=C(C1)C1=C(C1)c1ccccc1-2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
CDC25B P30305 2/20 0.42
MAPK1 P28482 3/20 0.40
CES1 P23141 3/20 0.40
NPC1 O15118 3/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
BCHE P06276 2/20 0.40
S100A4 P26447 2/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.40
MAPT P10636 2/20 0.40
RAB9A P51151 2/20 0.40
CES2 O00748 1/20 0.40
APAF1 O14727 1/20 0.40
TERT O14746 1/20 0.40
PLIN1 O60240 1/20 0.40
TDP2 O95551 1/20 0.40
S1PR4 O95977 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3302659 0.93 MAOA (0.48) MAOAMEN1KMT2ACDC25BMAPK1
SCHEMBL7426079 0.75 APAF1 (0.43) MAOAMEN1KMT2ACDC25BMAPK1
SCHEMBL28904690 0.73 MEN1 (0.61) MAOAMEN1KMT2ACDC25BMAPK1
SCHEMBL28694051 0.73 MEN1 (0.61) MAOAMEN1KMT2ACDC25BMAPK1
SCHEMBL29711875 0.73 MEN1 (0.61) MAOAMEN1KMT2ACDC25BMAPK1
SCHEMBL58152 0.73 MEN1 (0.61) MAOAMEN1KMT2ACDC25BMAPK1
SCHEMBL4368339 0.73 MEN1 (0.61) MAOAMEN1KMT2ACDC25BMAPK1
SCHEMBL49870 0.73 MEN1 (0.61) MAOAMEN1KMT2ACDC25BMAPK1
SCHEMBL29543474 0.73 MEN1 (0.61) MAOAMEN1KMT2ACDC25BMAPK1
SCHEMBL11875421 0.73 MEN1 (0.61) MAOAMEN1KMT2ACDC25BMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5358991-A Blended polyethylenes of varying densities, polypropylene lubricant, brominated and chlorinated flame retardants, mixtures of antimony oxide with zinc borate, stannate, stearate or ammonium octamolybdate, hindered stabilizers BELDEN WIRE & CABLE COMPANY (US) 1994-10-25 US claimed
EP-0060824-B1 FLAME-RETARDANT MOLDING COMPOSITIONS COMPRISING A COPOLYMER OF A VINYLAROMATIC MONOMER AND AN UNSATURATED DICARBOXYLIC ACID ANHYDRIDE, POLYVINYL CHLORIDE AND A GRAFT POLYMER MONSANTO COMPANY (US) 1986-05-28 EP claimed
EP-0009936-B1 FIRE RETARDANT POLYMERS AND A PROCESS FOR PRODUCING SUCH POLYMERS MONSANTO COMPANY (US) 1983-02-23 EP claimed
EP-0060824-A2 Flame-retardant molding compositions comprising a copolymer of a vinylaromatic monomer and an unsaturated dicarboxylic acid anhydride, polyvinyl chloride and a graft polymer MONSANTO COMPANY (US) 1982-09-22 EP claimed
US-4329272-A POLYVINYL CHLORIDE, GRAFT POLYMERS MONSANTO COMPANY (US) 1982-05-11 US claimed
US-5770820-A ATLEAST ONE TWISTED PAIR CONDUCTOR HAS NONFLUORINATED INSULATING MATERIAL SELECTED FROM FLAME RETARDANT POLYETHYLENE AND POLYPROPYLENE AND OTHER IS FLUORINATED POLYMER BELDEN TECHNOLOGIES, INC. 1998-06-23 US disclosed
US-5744757-A Plenum cable BELDEN WIRE & CABLE COMPANY (US) 1998-04-28 US disclosed
US-5525757-A USED IN PLENUM CABLES BELDEN WIRE & CABLE CO. (US) 1996-06-11 US disclosed
US-5514837-A Plenum cable BELDEN WIRE & CABLE COMPANY (US) 1996-05-07 US disclosed
EP-0060824-A2 Flame-retardant molding compositions comprising a copolymer of a vinylaromatic monomer and an unsaturated dicarboxylic acid anhydride, polyvinyl chloride and a graft polymer MONSANTO COMPANY (US) 1982-09-22 EP disclosed
US-4329272-A POLYVINYL CHLORIDE, GRAFT POLYMERS MONSANTO COMPANY (US) 1982-05-11 US disclosed