Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552162 | 0.80 | RARB (0.50) | CYP3A4CYP2C8S1PR3CYP2D6CYP2C9 | |
| SCHEMBL7118001 | 0.80 | RARB (0.50) | CYP3A4CYP2C8S1PR3CYP2D6CYP2C9 | |
| SCHEMBL8552427 | 0.80 | RARB (0.50) | CYP3A4CYP2C8S1PR3CYP2D6CYP2C9 | |
| SCHEMBL8557226 | 0.77 | MAPT (0.50) | CYP3A4CYP2C8S1PR3CYP2D6CYP2C9 | |
| SCHEMBL8558587 | 0.77 | FYN (0.36) | CYP3A4CYP2C8S1PR3CYP2D6CYP2C9 | |
| SCHEMBL8552620 | 0.77 | CYP3A4 (0.38) | CYP3A4CYP2C8S1PR3CYP2D6CYP2C9 | |
| SCHEMBL8542748 | 0.76 | FYN (0.40) | CYP3A4CYP2C8S1PR3CYP2D6CYP2C9 | |
| SCHEMBL8551722 | 0.76 | FYN (0.40) | CYP3A4CYP2C8S1PR3CYP2D6CYP2C9 | |
| SCHEMBL8553176 | 0.75 | CYP3A4 (0.46) | CYP3A4CYP2C8S1PR3CYP2D6CYP2C9 | |
| SCHEMBL8554004 | 0.75 | CYP3A4 (0.38) | CYP3A4CYP2C8S1PR3CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546338-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5385692-A | Improved response | CANON KABUSHIKI KAISHA (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0546338-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1993-06-16 | — | — | EP | disclosed |