SCHEMBL8552620

SCHEMBL8552620

CCCCCCCCc1ccc(-c2ccc3c(c2)CC(CCCCCCCC)C3)nn1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.38
CYP2C8 P10632 2/20 0.38
S1PR3 Q99500 2/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
KCNH2 Q12809 1/20 0.33
FYN P06241 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
MAPT P10636 1/20 0.32
STAT3 P40763 1/20 0.32
ATM Q13315 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HTR2A P28223 4/20 0.31
MCHR1 Q99705 4/20 0.31
CHRM1 P11229 1/20 0.31
S1PR1 P21453 4/20 0.30
S1PR4 O95977 1/20 0.30
S1PR5 Q9H228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8556156 0.91 CYP3A4 (0.40) CYP3A4CYP2C8S1PR3CYP2D6CYP2C9
SCHEMBL8552673 0.91 CYP3A4 (0.40) CYP3A4CYP2C8S1PR3CYP2D6CYP2C9
SCHEMBL8553142 0.80 RAB9A (0.55) CYP3A4CYP2C8S1PR3CYP2D6CYP2C9
SCHEMBL8553176 0.77 CYP3A4 (0.46) CYP3A4CYP2C8S1PR3CYP2D6CYP2C9
SCHEMBL9085051 0.77 RAB9A (0.37) KCNH2NPC1RAB9AMAPTSTAT3
SCHEMBL9082545 0.77 RAB9A (0.37) KCNH2NPC1RAB9AMAPTSTAT3
SCHEMBL8554498 0.77 CYP3A4 (0.39) CYP3A4CYP2C8S1PR3CYP2D6CYP2C9
SCHEMBL8553264 0.76 CYP3A4 (0.38) CYP3A4CYP2C8S1PR3CYP2D6CYP2C9
SCHEMBL8556271 0.76 NPC1 (0.47) CYP3A4CYP2C8S1PR3CYP2D6CYP2C9
SCHEMBL9162367 0.76 RAB9A (0.44) NPC1RAB9AMAPTSTAT3ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0546338-B1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1998-02-04 EP disclosed
US-5385692-A Improved response CANON KABUSHIKI KAISHA (JP) 1995-01-31 US disclosed
EP-0546338-A1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1993-06-16 EP disclosed