SCHEMBL855450

SCHEMBL855450

O=C1OC(=O)c2c1ccc(Cl)c2Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYMS P04818 2/20 0.50
ALDH1A1 P00352 3/20 0.46
TSHR P16473 1/20 0.46
TDP1 Q9NUW8 2/20 0.42
ALOX15 P16050 1/20 0.42
CES1 P23141 2/20 0.38
AHR P35869 3/20 0.34
MAPT P10636 2/20 0.33
HTR2A P28223 2/20 0.33
HTR2C P28335 2/20 0.33
HTR2B P41595 2/20 0.33
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
THRB P10828 1/20 0.33
APEX1 P27695 1/20 0.33
RECQL P46063 1/20 0.33
RAB9A P51151 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29462450 1.00 TYMS (0.50) TYMSALDH1A1TSHRTDP1ALOX15
Fluoride Ion SCHEMBL11260088 0.96 TYMS (0.47) TYMSALDH1A1TSHRTDP1ALOX15
SCHEMBL8849279 0.79 ALDH1A1 (0.43) TYMSALDH1A1TSHRTDP1ALOX15
SCHEMBL9771012 0.79 ALDH1A1 (0.43) TYMSALDH1A1TSHRTDP1ALOX15
SCHEMBL855172 0.79 ALDH1A1 (0.43) TYMSALDH1A1TSHRTDP1ALOX15
SCHEMBL8849276 0.79 TYMS (0.47) TYMSALDH1A1TSHRTDP1ALOX15
SCHEMBL9284604 0.79 TYMS (0.47) TYMSALDH1A1TSHRTDP1ALOX15
SCHEMBL9638008 0.78 TYMS (0.46) TYMSALDH1A1TSHRTDP1ALOX15
SCHEMBL29245225 0.76 TSHR (0.40) TYMSALDH1A1TSHRTDP1ALOX15
SCHEMBL8764869 0.76 ALDH1A1 (0.47) TYMSALDH1A1TSHRTDP1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12415892-B2 Polyimide film preparation method and application thereof INSTITUTE OF CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2025-09-16 US claimed
CN-120041182-A Particle size-controllable epoxy resin fracturing propping agent and preparation method thereof 江苏扬农化工集团有限公司 2025-05-27 CN claimed
CN-119752183-A Preparation method of epoxy resin fracturing propping agent with high heat resistance and low breakage rate 江苏扬农化工集团有限公司 2025-04-04 CN claimed
CN-117430812-A Photosensitive polyamic acid ester resin, resin composition and application 明士(北京)新材料开发有限公司 2024-01-23 CN claimed
CN-117219793-A Preparation method and application of porous carbon nickel catalyst for fuel cell 北京科技大学 2023-12-12 CN claimed
CN-114230792-B Positive photosensitive polyimide resin, resin composition, and preparation method and application thereof 明士(北京)新材料开发有限公司 2023-10-03 CN claimed
CN-116826021-A Porous hard carbon composite material and preparation method and application thereof 江苏钠博恩新材料有限公司 2023-09-29 CN claimed
CN-115437218-A Photosensitive resin with symmetrical and asymmetrical structures and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-12-06 CN claimed
CN-114995060-B Negative photosensitive resin composition capable of being cured at low temperature and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-11-01 CN claimed
CN-114995060-A Negative photosensitive resin composition capable of being cured at low temperature and preparation method and application thereof 明士(北京)新材料开发有限公司 2022-09-02 CN claimed
US-6066743-A Solventless preparation of phthalimides GENERAL ELECTRIC COMPANY (US) 2000-05-23 US claimed
WO-2000005194-A1 PROCESS FOR THE PREPARATION OF 1,4-BIS[[2- (DIMETHYLAMINO) ETHYL] AMINO] -5,8- DIHYDROXYANTHRACENE- 9,10-DIONE BTG INTERNATIONAL LIMITED (GB) 2000-02-03 WO claimed
US-5683553-A PURIFICATION FROM MIXTURE WITH 4,5-DICHLOROPHTHALIC ANHYDRIDE BASF AKTIENGESELLSCHAFT (DE) 1997-11-04 US claimed
EP-0510492-B1 Photochlorination of phthalic anhydride OCCIDENTAL CHEM CO (US) 1995-07-05 EP claimed
EP-0401589-B1 Method of producing imide bond-containing resins DAI ICHI KOGYO SEIYAKU CO LTD (JP) 1994-10-26 EP claimed
US-5300201-A Mixing with chlorine, irradiating; selective formation of 4-chloro phthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1994-04-05 US claimed
EP-0510492-A1 Photochlorination of phthalic anhydride OCCIDENTAL CHEMICAL CORPORATION (US) 1992-10-28 EP claimed
US-5086114-A Reacting anhydride-containing copolymer with diisocyanate and halogenated phthalic anhydride in the prense of quaternary phosphonium compound DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1992-02-04 US claimed
US-4981999-A Selective removal of chlorine from chlorophthalic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1991-01-01 US claimed
EP-0401589-A2 Method of producing imide bond-containing resins DAI-ICHI KOGYO SEIYAKU CO., LTD. (JP) 1990-12-12 EP claimed