SCHEMBL8764869

SCHEMBL8764869

O=Cc1c(Cl)ccc2c1C(=O)OC2=O

nearest known ligand 0.47

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.47
TDP1 Q9NUW8 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TYMS P04818 2/20 0.44
TSHR P16473 1/20 0.40
ALOX15 P16050 1/20 0.37
ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9284604 0.77 TYMS (0.47) ALDH1A1TDP1TYMSTSHRALOX15
SCHEMBL29462450 0.76 TYMS (0.50) ALDH1A1TDP1MEN1KMT2ATYMS
SCHEMBL855450 0.76 TYMS (0.50) ALDH1A1TDP1MEN1KMT2ATYMS
SCHEMBL29132827 0.74 ALDH1A1 (0.40) ALDH1A1TDP1MEN1KMT2ATYMS
SCHEMBL8849276 0.73 TYMS (0.47) ALDH1A1TDP1TYMSTSHRALOX15
Fluoride Ion SCHEMBL11260088 0.73 TYMS (0.47) ALDH1A1TDP1MEN1KMT2ATYMS
SCHEMBL8055705 0.73 ADORA2A (0.47) ALDH1A1TDP1MEN1KMT2AALOX15
SCHEMBL9638008 0.72 TYMS (0.46) ALDH1A1TDP1MEN1KMT2ATYMS
SCHEMBL542 0.70 TSHR (0.52) ALDH1A1TDP1TYMSTSHRALOX15
SCHEMBL29555800 0.70 TSHR (0.52) ALDH1A1TDP1TYMSTSHRALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4305105-A1 THERMOPLASTIC COMPOSITIONS SHPP Global Technologies B.V. (NL) 2024-01-17 EP disclosed
CN-117055293-A Photosensitive polyimide composition, method for producing pattern, and electronic component 江苏艾森半导体材料股份有限公司 2023-11-14 CN disclosed
CN-115826360-B Photosensitive polyimide composition, method for producing pattern, cured product, and electronic component 江苏艾森半导体材料股份有限公司 2023-09-12 CN disclosed
WO-2022189998-A1 THERMOPLASTIC COMPOSITIONS SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2022-09-15 WO disclosed
CN-105793344-B Flame retardant thermoplastic compositions with improved properties 沙特基础工业全球技术公司 2019-01-01 CN disclosed
EP-0732355-B1 Coated thermoplastic articles GEN ELECTRIC (US) 1997-07-16 EP disclosed
US-5605754-A PROTECTIVE COATING CONTAINING TRIHYDRICPHENOL-BENZOTRIAZOLE COMPOUND GENERAL ELECTRIC COMPANY (US) 1997-02-25 US disclosed
EP-0732355-A1 Coated polycarbonate articles GENERAL ELECTRIC COMPANY (US) 1996-09-18 EP disclosed
EP-0305718-B1 POLYCARBONATE-POLYISOBUTYLENE BLOCK COPOLYMER GENERAL ELECTRIC COMPANY (US) 1993-09-29 EP disclosed
US-5041502-A Oxidizing butadiene-isobutylene or isoprene-isobutylene copolymers GENERAL ELECTRIC COMPANY (US) 1991-08-20 US disclosed
US-4994526-A Thermoplastic molding material GENERAL ELECTRIC COMPANY (US) 1991-02-19 US disclosed
US-4871830-A IMPACT STRENGTH MARK VICTOR (US) 1989-10-03 US disclosed
US-4845158-A MOLDING MATERIALS, AUTOMOBILES, HEAT RESISTANCE GENERAL ELECTRIC COMPANY (US) 1989-07-04 US disclosed
EP-0305718-A2 Polycarbonate-polyisobutylene block copolymer GENERAL ELECTRIC COMPANY (US) 1989-03-08 EP disclosed
US-4728716-A ADDITION-CONDENSATION BLOCK COPOLYMERS GENERAL ELECTRIC COMPANY (US) 1988-03-01 US disclosed