Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.63 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.63 |
| ▸ | CHRNB2 | P17787 | 8/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 8/20 | 0.57 |
| ▸ | AKT1 | P31749 | 1/20 | 0.55 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.54 |
| ▸ | CHRNG | P07510 | 1/20 | 0.54 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.54 |
| ▸ | CHRND | Q07001 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7827331 | 0.99 | CHRNB4 (0.62) | CHRNB4CHRNA3CHRNB2CHRNA4AKT1 | |
| SCHEMBL7419252 | 0.91 | CHRNB2 (0.60) | CHRNB2CHRNA4 | |
| SCHEMBL7408630 | 0.91 | CHRNB2 (0.60) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7409809 | 0.90 | CHRNB2 (0.59) | CHRNB2CHRNA4 | |
| SCHEMBL9239044 | 0.81 | CHRNB4 (0.62) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL9243580 | 0.81 | CHRNB4 (0.62) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| SCHEMBL9239052 | 0.81 | CHRNB4 (0.62) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL9240140 | 0.80 | CHRNB4 (0.61) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL9240142 | 0.80 | CHRNB4 (0.61) | CHRNB4CHRNA3CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL9243429 | 0.80 | CHRNB4 (0.61) | CHRNB4CHRNA3CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846114-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1996040682-A1 | 3-PYRIDYLOXYALKYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1996-12-19 | — | — | WO | disclosed |