Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 2/20 | 0.62 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.62 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 2/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9239044 | 1.00 | CHRNB4 (0.62) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| SCHEMBL9243580 | 1.00 | CHRNB4 (0.62) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| Hydrochloric Acid SCHEMBL9240142 | 0.99 | CHRNB4 (0.61) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| Hydrochloric Acid SCHEMBL9240140 | 0.99 | CHRNB4 (0.61) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| Hydrochloric Acid SCHEMBL9243429 | 0.99 | CHRNB4 (0.61) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| SCHEMBL9239686 | 0.91 | CHRNA3 (0.59) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| SCHEMBL9239680 | 0.91 | CHRNA3 (0.59) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| SCHEMBL27589827 | 0.88 | CHRNB2 (0.51) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| SCHEMBL9244564 | 0.83 | CHRNB4 (0.54) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH | |
| SCHEMBL9244561 | 0.83 | CHRNB4 (0.54) | CHRNB4CHRNA3CHRNB2CHRNA4FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5472958-A | 2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function | ABBOTT LABORATORIES (US) | 1995-12-05 | — | — | US | claimed |
| US-5472958-A | 2-((nitro)phenoxymethyl) heterocyclic compounds that enhance cognitive function | ABBOTT LABORATORIES (US) | 1995-12-05 | — | — | US | disclosed |