Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 8/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 7/20 | 0.39 |
| ▸ | RXRG | P48443 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | C5 | P01031 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552468 | 0.91 | NR4A2 (0.39) | RXRANR4A2NR4A1NR4A3RXRB | |
| SCHEMBL8554766 | 0.90 | KDR (0.45) | RXRANR4A2NR4A1NR4A3RXRB | |
| SCHEMBL8552619 | 0.86 | SLC29A1 (0.53) | RXRANR4A2NR4A1NR4A3RXRB | |
| SCHEMBL8554772 | 0.86 | SLC29A1 (0.53) | RXRANR4A2NR4A1NR4A3RXRB | |
| SCHEMBL8598990 | 0.86 | SLC29A1 (0.45) | RXRANR4A2NR4A1NR4A3RXRB | |
| SCHEMBL8552887 | 0.85 | NR4A2 (0.47) | RXRANR4A2NR4A1NR4A3RXRB | |
| SCHEMBL8414147 | 0.83 | SLC29A1 (0.43) | RXRANR4A2NR4A1NR4A3RXRB | |
| Hydrochloric Acid SCHEMBL8595835 | 0.83 | SLC29A1 (0.43) | RXRANR4A2NR4A1NR4A3RXRB | |
| SCHEMBL8558999 | 0.81 | NR4A2 (0.44) | RXRANR4A2NR4A1NR4A3RXRB | |
| SCHEMBL8556121 | 0.81 | NR4A2 (0.44) | RXRANR4A2NR4A1NR4A3RXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |
| US-5382584-A | Antiischemic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-17 | — | — | US | claimed |
| EP-0582164-A1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | Bristol-Myers Squibb Company (US) | 1994-02-09 | — | — | EP | claimed |