Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 8/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 10/20 | 0.39 |
| ▸ | RXRB | P28702 | 10/20 | 0.39 |
| ▸ | RXRG | P48443 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | C5 | P01031 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554772 | 0.93 | SLC29A1 (0.53) | KDRSLC29A1KDM4ELMNANR4A2 | |
| SCHEMBL8552619 | 0.93 | SLC29A1 (0.53) | KDRSLC29A1KDM4ELMNANR4A2 | |
| SCHEMBL8598990 | 0.92 | SLC29A1 (0.45) | KDRSLC29A1KDM4ELMNANR4A2 | |
| SCHEMBL8554585 | 0.90 | RXRA (0.43) | SLC29A1KDM4ELMNANR4A2NR4A1 | |
| SCHEMBL8414147 | 0.89 | SLC29A1 (0.43) | KDRSLC29A1KDM4ELMNANR4A2 | |
| Hydrochloric Acid SCHEMBL8595835 | 0.89 | SLC29A1 (0.43) | KDRSLC29A1KDM4ELMNANR4A2 | |
| SCHEMBL8553498 | 0.86 | SLC29A1 (0.49) | KDRSLC29A1KDM4ELMNANR4A2 | |
| SCHEMBL8553960 | 0.85 | SLC29A1 (0.59) | SLC29A1RXRARXRBRXRGALDH1A1 | |
| SCHEMBL8554568 | 0.85 | KDR (0.58) | KDRKDM4ELMNANR4A2NR4A1 | |
| SCHEMBL9410500 | 0.85 | SLC29A1 (0.41) | SLC29A1KDM4ELMNANR4A2NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |
| EP-0582164-A1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | Bristol-Myers Squibb Company (US) | 1994-02-09 | — | — | EP | claimed |