Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 7/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 4/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
| ▸ | RXRB | P28702 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554585 | 0.91 | RXRA (0.43) | NR4A2NR4A1NR4A3RXRASCN4A | |
| SCHEMBL8552887 | 0.84 | NR4A2 (0.47) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL8554766 | 0.81 | KDR (0.45) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL8556121 | 0.81 | NR4A2 (0.44) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL8558999 | 0.81 | NR4A2 (0.44) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL8555365 | 0.78 | KDM4E (0.40) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL8552619 | 0.78 | SLC29A1 (0.53) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL8554772 | 0.78 | SLC29A1 (0.53) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL8555057 | 0.78 | NR4A2 (0.51) | NR4A2NR4A1NR4A3RXRARXRB | |
| SCHEMBL8598990 | 0.77 | SLC29A1 (0.45) | NR4A2NR4A1NR4A3RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |