Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.50 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.47 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.47 |
| ▸ | RPS17 | P08708 | 1/20 | 0.47 |
| ▸ | RPSA | P08865 | 1/20 | 0.47 |
| ▸ | RPS2 | P15880 | 1/20 | 0.47 |
| ▸ | RPL35A | P18077 | 1/20 | 0.47 |
| ▸ | RPL7 | P18124 | 1/20 | 0.47 |
| ▸ | RPL17 | P18621 | 1/20 | 0.47 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.47 |
| ▸ | RPS3 | P23396 | 1/20 | 0.47 |
| ▸ | RPS12 | P25398 | 1/20 | 0.47 |
| ▸ | RPL13 | P26373 | 1/20 | 0.47 |
| ▸ | RPL10 | P27635 | 1/20 | 0.47 |
| ▸ | RPL12 | P30050 | 1/20 | 0.47 |
| ▸ | RPL9; RPL9P7; RPL9P8; RPL9P9 | P32969 | 1/20 | 0.47 |
| ▸ | RPL22 | P35268 | 1/20 | 0.47 |
| ▸ | RPL4 | P36578 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1445588 | 0.87 | PDE10A (0.66) | PDE3BPDE3APDE10AKCNH2ALDH1A1 | |
| Water SCHEMBL28228890 | 0.85 | PDE10A (0.64) | PDE3BPDE3APDE10AKCNH2ALDH1A1 | |
| SCHEMBL31756882 | 0.82 | ACHE (0.55) | KCNH2ALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL7073972 | 0.82 | ACHE (0.55) | KCNH2ALDH1A1HPGDKDM4ERAB9A | |
| Bromide SCHEMBL8857652 | 0.81 | ACHE (0.53) | KCNH2ALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL8554954 | 0.77 | PDE10A (0.53) | PDE3BPDE3APDE10AKCNH2ALDH1A1 | |
| SCHEMBL1445495 | 0.76 | PDE10A (0.44) | PDE3BPDE3APDE10AKCNH2ALDH1A1 | |
| SCHEMBL1446013 | 0.75 | ACHE (0.48) | PDE3BPDE3APDE10AKCNH2ALDH1A1 | |
| SCHEMBL8148735 | 0.75 | AKR1B1 (0.65) | ALDH1A1HPGDKDM4ERAB9ALMNA | |
| SCHEMBL10477025 | 0.74 | ACHE (0.53) | ALDH1A1HPGDKDM4ERAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0617022-B1 | 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound | BANYU PHARMA CO LTD (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0617022-A1 | 6,7, dialkoxy-3,4-dihydroisoquinolin-8-ol, process for preparation thereof and process for preparation of 6,7-dialkoxy-1,2,3,4-tetrahydroisoquinolin-8-ol using the compound | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-09-28 | — | — | EP | disclosed |