Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553082 | 0.86 | KIF11 (0.52) | KIF11PARP1RAB9AKMT2ANPC1 | |
| SCHEMBL8557670 | 0.84 | KMT2A (0.53) | KIF11PARP1RAB9AKMT2ANPC1 | |
| SCHEMBL8552714 | 0.84 | KIF11 (0.49) | KIF11PARP1RAB9AKMT2ANPC1 | |
| SCHEMBL31498185 | 0.80 | NR4A2 (0.58) | NR4A2SMN1; SMN2HPGDLMNAALDH1A1 | |
| SCHEMBL7831236 | 0.79 | GAA (0.67) | NR4A2RAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7835186 | 0.79 | GAA (0.63) | NR4A2RAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7834393 | 0.79 | MAPT (0.54) | NR4A2RAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7419884 | 0.79 | KIF11 (0.58) | KIF11NR4A2PARP1RAB9AKMT2A | |
| SCHEMBL6315808 | 0.78 | GAA (0.74) | NR4A2RAB9AKMT2ANPC1SMN1; SMN2 | |
| SCHEMBL7422570 | 0.78 | KIF11 (0.55) | KIF11NR4A2PARP1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |