Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557670 | 0.91 | KMT2A (0.53) | KIF11PARP1ALOX5KMT2AMEN1 | |
| SCHEMBL8552714 | 0.88 | KIF11 (0.49) | KIF11PARP1ALOX5KMT2AMEN1 | |
| SCHEMBL8554616 | 0.86 | KIF11 (0.54) | KIF11PARP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7422740 | 0.81 | KIF11 (0.55) | KIF11PARP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7415956 | 0.80 | KIF11 (0.53) | KIF11PARP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7467512 | 0.78 | KIF11 (0.51) | KIF11PARP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7416246 | 0.77 | ALOX5 (0.44) | KIF11ALOX5KMT2AMEN1ALDH1A1 | |
| SCHEMBL7418110 | 0.76 | KMT2A (0.58) | KIF11PARP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL2486166 | 0.74 | KIF11 (0.63) | KIF11PARP1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7409075 | 0.74 | KMT2A (0.55) | KIF11PARP1KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |