Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.70 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | DRD4 | P21917 | 4/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9304050 | 0.99 | ALOX5 (0.69) | ALOX5HTR2AHTR2CDRD3DRD4 | |
| SCHEMBL8557565 | 0.95 | ALOX5 (0.77) | ALOX5HTR2AHTR2CDRD3DRD4 | |
| Hydrochloric Acid SCHEMBL8555007 | 0.94 | ALOX5 (0.75) | ALOX5HTR2AHTR2CDRD3DRD4 | |
| SCHEMBL8554776 | 0.93 | ALOX5 (0.73) | ALOX5HTR2AHTR2CDRD3DRD4 | |
| Hydrochloric Acid SCHEMBL8555946 | 0.92 | ALOX5 (0.71) | ALOX5HTR2AHTR2CDRD3DRD4 | |
| SCHEMBL8560149 | 0.85 | ALOX5 (0.63) | ALOX5HTR2AHTR2CDRD3DRD4 | |
| SCHEMBL8557119 | 0.84 | ALOX5 (0.64) | ALOX5HTR2AHTR2CDRD3DRD4 | |
| SCHEMBL9305812 | 0.84 | ALOX5 (0.63) | ALOX5HTR2AHTR2CDRD3DRD4 | |
| SCHEMBL8552282 | 0.84 | ALOX5 (0.59) | ALOX5HTR2AHTR2CBCL2L1MCL1 | |
| SCHEMBL9305806 | 0.83 | ALOX5 (0.62) | ALOX5HTR2AHTR2CDRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0529452-B1 | 1,7-Condensed 3-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | SOLVAY PHARM GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5324725-A | Antiinflammatory agent, antiallergen | KALI-CHEMIE PHARMA GMBH (DE) | 1994-06-28 | — | — | US | disclosed |
| EP-0529452-A2 | 1,7-Condensed 2-(piperazinoalkyl)indol derivatives, process and intermediates for their preparation and pharmaceutical compositions containing them | Kali-Chemie Pharma GmbH (DE) | 1993-03-03 | — | — | EP | disclosed |