Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CD69 | Q07108 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217544 | 0.85 | CD69 (0.45) | TSHRCD69KMT2AMAPTNPSR1 | |
| SCHEMBL15541243 | 0.76 | KDM4E (0.43) | TSHRCD69TUBB4ATUBBTUBA3C | |
| SCHEMBL28218043 | 0.76 | SLC6A3 (0.57) | TSHRSLC6A3KMT2AMAPTNPSR1 | |
| SCHEMBL9643432 | 0.76 | KMT2A (0.55) | TSHRSLC6A3KMT2AMAPTNPSR1 | |
| Hydroxyamine SCHEMBL11037119 | 0.74 | CD69 (0.44) | TSHRCD69TUBB4ATUBBTUBA3C | |
| SCHEMBL9425229 | 0.74 | SLC6A3 (0.55) | TSHRSLC6A3KMT2AMAPTNPSR1 | |
| SCHEMBL5551848 | 0.74 | LMNA (0.64) | TSHRSLC6A3KMT2AMAPTNPSR1 | |
| SCHEMBL9514205 | 0.72 | SMN1; SMN2 (0.56) | TSHRSLC6A3KMT2AMAPTNPSR1 | |
| Fluorene SCHEMBL2708609 | 0.71 | TSHR (0.68) | TSHRSLC6A3KMT2AMAPTKDM4E | |
| Fluorene SCHEMBL27412062 | 0.71 | TSHR (0.68) | TSHRSLC6A3KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572599-B1 | ION-SENSITIVE DYES | KODAK LTD (GB) | 1998-06-17 | — | — | EP | disclosed |
| US-5641684-A | Ion-sensitive dyes | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1997-06-24 | — | — | US | disclosed |
| EP-0572599-A1 | ION-SENSITIVE DYES | KODAK LIMITED (GB) | 1993-12-08 | — | — | EP | disclosed |
| WO-1993012428-A1 | ION-SENSITIVE DYES | KODAK LIMITED (GB) | 1993-06-24 | — | — | WO | disclosed |