Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | MOK | Q9UQ07 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554243 | 0.66 | BCHE (0.37) | KDM4EGAASMN1; SMN2 | |
| SCHEMBL4149685 | 0.66 | KMT2A (0.51) | ADORA3HSD17B10TP53KDM4EMAPT | |
| SCHEMBL11727405 | 0.65 | MAPT (0.51) | ADORA3ADORA2AADORA1HSD17B10KDM4E | |
| SCHEMBL8554652 | 0.64 | HSD17B10 (0.34) | HSD17B10TP53KDM4EMAPTALDH1A1 | |
| SCHEMBL8554648 | 0.64 | KCNH2 (0.49) | KDM1A | |
| SCHEMBL4163110 | 0.63 | KMT2A (0.66) | ADORA3HSD17B10TP53KDM4EMAPT | |
| SCHEMBL4159315 | 0.63 | KDM4E (0.66) | ADORA3HSD17B10KDM4EMAPTALDH1A1 | |
| Aminacrine SCHEMBL22830340 | 0.61 | KDM4E (0.69) | ADORA3HSD17B10TP53KDM4EMAPT | |
| SCHEMBL3074031 | 0.61 | KDM4E (0.71) | ADORA3HSD17B10KDM4EMAPTALDH1A1 | |
| Aminacrine SCHEMBL31084227 | 0.61 | KDM4E (0.69) | ADORA3HSD17B10TP53KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543307-B1 | Nootropic agent | SANWA KAGAKU KENKYUSHO CO (JP) | 1998-05-06 | — | — | EP | claimed |
| US-5434165-A | Nootropic agents, compositions of, and method of use thereof | SANAWA KAGAKU KENKYUSHO COMPANY, LTD. (JP) | 1995-07-18 | — | — | US | claimed |