Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 19/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 16/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 16/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6197410 | 0.94 | ADRA1A (0.49) | ADRA1AADRA1DADRA1BDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6200207 | 0.93 | ADRA1A (0.49) | ADRA1AADRA1DADRA1BDRD2DRD4 | |
| SCHEMBL7796529 | 0.92 | ADRA1A (0.54) | ADRA1AADRA1DADRA1BDRD2DRD4 | |
| Cadaverine Tartrate SCHEMBL8136242 | 0.89 | ADRA1A (0.52) | ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL6646907 | 0.89 | ADRA1A (0.55) | ADRA1AADRA1DADRA1BDRD2 | |
| Hydrochloric Acid SCHEMBL6787204 | 0.84 | ADRA1A (0.58) | ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9055621 | 0.84 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BDRD2DRD4 | |
| SCHEMBL6732872 | 0.84 | ADRA1A (0.48) | ADRA1AADRA1DADRA1BDRD2DRD4 | |
| SCHEMBL7640674 | 0.83 | ADRA1A (0.59) | ADRA1AADRA1DADRA1BDRD2 | |
| SCHEMBL6729949 | 0.82 | ADRA1A (0.63) | ADRA1AADRA1DADRA1BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0790826-A4 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMA CORP (US) | 1998-11-11 | — | — | EP | disclosed |
| EP-0790826-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1997-08-27 | — | — | EP | disclosed |