Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 15/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 12/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 12/20 | 0.44 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554719 | 0.92 | ADRA1A (0.55) | ADRA1AADRA1DADRA1BDRD2DRD4 | |
| Cadaverine Tartrate SCHEMBL8136242 | 0.88 | ADRA1A (0.52) | ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL9055621 | 0.87 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BDRD2DRD4 | |
| SCHEMBL6197410 | 0.85 | ADRA1A (0.49) | ADRA1AADRA1DADRA1BDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6200207 | 0.85 | ADRA1A (0.49) | ADRA1AADRA1DADRA1BDRD2DRD4 | |
| SCHEMBL6729949 | 0.84 | ADRA1A (0.63) | ADRA1AADRA1DADRA1BDRD2MCHR1 | |
| SCHEMBL6732872 | 0.82 | ADRA1A (0.48) | ADRA1AADRA1DADRA1BDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL6199371 | 0.82 | ADRA1A (0.52) | ADRA1AADRA1DADRA1BDRD2DRD4 | |
| SCHEMBL7640674 | 0.82 | ADRA1A (0.59) | ADRA1AADRA1DADRA1BDRD2MCHR1 | |
| Hydrochloric Acid SCHEMBL6787204 | 0.82 | ADRA1A (0.58) | ADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010041707-A1 | Dihydropyrimidines and uses thereof | MERCK AND CO., INC | 2001-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010041707-A1 | Dihydropyrimidines and uses thereof | QDPR, DPYD, ADRA1D | ADRA1A 4/4885ADRA1D 3/4885ADRA1B 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.